Transaction volume hit 1.47 million last month.
OneChicago offers single stock futures on approximately 1,800 equities, including American depository receipts and exchange-traded funds.
The exchange's flagship OCX.NoDivRisk products continued to garner 98 percent of month-end open interest.
OCX.NoDivRisk products, which are an equity finance tool that promise to remove dividend risk for customers carrying synthetic equity delta exposure, saw its notional value increased 133 percent to $5.68 billion, year-over-year for March.
According to OneChicago, the growth is primarily due to the increased use of weekly futures to transition delta exposure from a capital-intensive cash equity position to the OneChicago futures.