Beginning in January 2018, Dijsselhof will replace Urs Rüegsegger, who announced he would be stepping down in May.
Prior to SIX, Dijsselhof has been Group COO for Euronext in Amsterdam since July 2014.
He has also held positions at ABN Amro Bank, Royal Bank of Scotland and ANZ Australia and New Zealand Banking Group in various markets, including Hong Kong and Singapore.
Dijsselhof will oversee a major restructuring of SIX operations, including a realignment of its securities financing, which will see a bundling of all activities in the securities businesses under one unit.
SIX plans to merge exchange trading and post-trading areas into one organisational unit, among other changes.
According to SIX, this realignment will strengthen the competitiveness of SIX and the Swiss financial centre.
SIX will focus consistently on infrastructure services for shareholders and the financial centre in securities, payments and financial information, which are the core business areas of SIX.
Commenting on Dijsselhof’s appointment, Romeo Lacher, chairman of the board of directors at SIX, said: "I am delighted to have found in Jos Dijsselhof an experienced manager for SIX with strong leadership qualities and an outstanding track record.”